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Bochaton-Piallat M-L, Gabbiani G, Hinz B

Studies using various bacterial strains have shown beneficial effects on obesity in a number of ways, including decreased inflammation of adipose tissue, endotoxemia, adiposity, body mass, leptin levels, and energy consumption

Appetite & Craving Control Helps reduce hunger, curb cravings, and increase feelings of fullness, supporting better portion control

Key deciding factors for initiation of oral or subcutaneous semaglutide included: patient preference (fear of injection)

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Notably, in newly diagnosed patients with overweight/obesity (BMI 25 kg/m), combination therapy with GLP-1RAs (e.g., semaglutide) and metformin has shown increased efficacy