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Although many ENS functions are independent of CNS input, the ENS does function as an interface to detect intestinal luminal cues that trigger upstream CNS signaling pathways
doi:10.1007/s12178-025-09980-9 Lai WC, Mange TR, Karasavvidis T, Lee YP, Wang D
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The non-greasy texture absorbs quickly, allowing you to continue your day comfortably after application.