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Thus, damage to mitochondrial DNA and loss of can further increase ROS production, thereby creating a cycle of dysfunction that includes increased ROS production by the respiratory chain, activation of signal transduction pathways, and potentially, leading to apoptosis or necrosis, as well as the release of cytochrome c, which triggers apoptosis

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Al-hijamah (wet cupping therapy of prophetic medicine) was done for him by an expert hijamatologist (a physician therapist) who did superficial scarifications using 10 large sucking cups (8 cups at the upper back and 2 cups at the right hypochondrium, and subcostal region)

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