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According to Kleinman et al., while TB-500 is likely to have additional uses in the skin and in injured organs for tissue repair and regeneration there is no research showing what dosage it may be administered to this end

Because NAD + reduction is frequently accompanied by impaired mitochondrial performance concomitant to tissue damage and dysfunction [20, 21], tissue NAD + restoration has been proposed as a promising therapeutic target in mitochondria-driven strategies to treat metabolic diseases [19]