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Based on receptor-mediated targeting, BDPR NSs can effectively cross the BBB, target dopaminergic neurons, specifically clear ROS and reduce iron aggregation in PD lesions, and exhibit good neuroprotective effects in PD cell, nematode, and mouse models (226)

36 GLP-1R GLP-1R, a member of the GPCR family, exhibits specific affinity for GLP-1

It is important to note that more research is needed to fully understand the cognitive function benefits of NAD+ therapy, and it is essential to work with a healthcare professional to determine if it is a suitable treatment option

Int J Epidemiol

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