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Based on a competitive inhibition mechanism, adding supraphysiological concentrations of glutamine (SPG) inhibited the uptake of neutral amino acids in oocytes expressing human SLC1A5 (ASCT2), the primary glutamine transporter in cancer cells [92,93]
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At the end of the study, the group with the larger dose had 30-35% more reduced glutathione in erythrocytes, lymphocytes and plasma while the smaller dose had 17% more in the blood and 29% more in erythrocytes
[12] This was followed by its entry into Ireland in 2020, [13] China in 2021, [14] and the United Arab Emirates in 2024
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