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Studies on GLP-1 users show those maintaining 0.71.0g of protein per pound of body weight lose more fat and less muscle compared to those in caloric deficit without adequate protein

Furthermore, the high fat content in many fast food items can exacerbate gastrointestinal side effects associated with GLP-1 medications, as noted in FDA Medication Guides

At 68 weeks, average reduction in body weight was 9.6% with the higher dose, 6.99% with the lower dose, and 3.42% with placebo

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GLP-1 and GIP receptor signaling in beta cells - A review of receptor interactions and co-stimulation