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Dickerson F, Stallings C, Origoni A, Vaughan C, Khushalani S, Yolken R

Chottekalapanda RU, et al

Phase I activates substances through reactions catalysed by cytochrome P450 enzymes, producing water-soluble metabolites

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In recent years, the glucagon-like peptide-1 receptor (GLP-1R) has emerged as an important target in the treatment of type II diabetes and obesity 6, 7