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In a rodent model of autism, probiotics decrease gut leakiness in relation to gene expression of GABA receptors: emphasize how crucial the gut-brain axis
Acknowledgments Funding: This work was supported by the National Key Research and Development Program of China (2023YFC2508200), the National Natural Science Foundation of China (82373509, 82003384, and 82203960), Fundamental Research Funds for the Central Universities (2022CDJYGRH-003 and 2023CDJKYJH066), the Natural Science Foundation of Chongqing (CSTB2023JXJL-YFX0028), Chongqing Talents: Exceptional Young Talents Project (cstc2021ycjh-bgzxm0197), Inheritance and Innovation Team of TCM Treatment of Immune Diseases, Scientific Research Foundation from Chongqing University (02210011044110), and Research Horizontal Projects of Chongqing University (H20231432 and H20230936), China
Under stress conditions, activated microglia release inflammatory factors that drive neuroinflammation, whereas in a tissue repair state, they promote neuroprotection ( 42 significantly increased TNF- mRNA expression, this effect was suppressed by choline deficiency and Lico E treatment
Weir MR, Bakris GL, Bushinsky DA, Mayo MR, Garza D, Stasiv Y, et al
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