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They may include: They may include: Nausea Vomiting Diarrhea Vomiting Diarrhea Constipation Abdominal pain Decreased appetite Abdominal pain Decreased appetite Indigestion Redness at injection site Redness at injection site Most symptoms improve over time

Many patients continue to experience symptoms long after discontinuing the medication

Its usually discovered by chance during routine investigations like a colonoscopy or other radiological procedures

The difference between a successful KLOW study and one that produces null results often comes down to storage discipline in the 28 days after reconstitution

Idiosyncratic drug hepatotoxicity

CMS wants lower spending (see graphic below for how much CMS is spending)