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Gubert, C

(Basel) 13 , 294 (2020)

In addition to the up-regulation of cytoskeletal proteins in platelets from -thalassemia/HbE patients, we observed the up-regulation of integrin, a transmembrane receptor protein that acts as a bridge between the extracellular matrix and the cytoskeletal membrane that mediates signal transduction in activated platelets, resulting in platelet shape changes and platelet aggregation 22

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Clonal BRAF mutations in melanocytic nevi and initiating role of BRAF in melanocytic neoplasia

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