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Given the lower HbA1c values achieved with once-weekly semaglutide 0.5 mg compared with dulaglutide 0.75 mg, the analysis is likely to be highly conservative from the longer-term perspective of a decision-maker covering both the initial drug costs and subsequent treatment of diabetes complications
The dark blue circles in the terminal portion of tirzepatide are amino acids from exenatide, a protein-derived peptide (exendin-4) present in the venom of the Gila monster ( Heloderma suspectum ) and known to activate the receptor GLP-1
Semaglutide (GLP-1) was originally developed to help people with type 2 diabetes manage their blood sugar levels
Conte C et al
If you take GLP-1 drugs to manage your weight or improve your health, you should be aware of the possible risks
Being aware of warning signs helps ensure that any concerns are assessed quickly and treatment is adjusted or stopped if needed
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