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Nevertheless, these data together paint a smoker epithelium that has been rendered more functionally monochromatic, collapsing on the secretory and proteosomal basal cell phenotypes at the expense of its normal defensive, interactive, and reparative roles essential to lung health and homeostasis

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In addition to the McEwan et al

The chorus reflects a sense of longing and hopelessness, as the narrator clings to the hope that things might improve, despite knowing deep down that they won't