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The compound of any one of the preceding clauses wherein the compound is of the formula EC 1669 The compound of any one of the preceding clauses wherein the compound is not of the formula EC 1669 A unit dose or unit dosage form composition comprising a therapeutically effective amount of one or more compounds of any one of the preceding clauses, optionally in combination with one or more carriers, diluents, or excipients, or a combination thereof

A DNA damage checkpoint response in telomere-initiated senescence