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This effect was then shown to be mimicked by GLP-1 that acted on the same receptor (94)

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Moreover, transgenic mice over-expressing SDF-1 become resistant to streptozotocin-induced diabetes (61), further suggesting that SDF-1 may have some metabolic effects

Mutations in Kelch-like 3 and cullin 3 cause hypertension and electrolyte abnormalities

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