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43, 44 Also, this pathway has been shown to induce BBB permeability following focal cerebral ischemia, 45 HIV-induced BBB disruption, 46 and traumatic brain injury

Similarly, animal studies have shown that compared with healthy controls, CKD rats with hypertension displayed decreased abundances of Ligilactobacillus and Ruminococcus but increased abundances of Eubacterium and Duncaniella [153]

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This spread into all muscle groups is the defining characteristic of ALS

Standard cycle: 46 weeks Extended cycle with monitoring: up to 12 weeks for complex or chronic presentations Rest period between cycles: 48 weeks is typical Duration matters because tissue remodeling continues for weeks after a cycle ends

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