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Eli Lilly says it is studying retatrutide as a treatment for obesity, type 2 diabetes, knee osteoarthritis pain, obstructive sleep apnea, chronic low back pain and liver disease

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MK-677 has been employed primarily in studies requiring sustained, measurable elevation of circulating IGF-1 over weeks to months

The SUMMIT Trial Participant profile: 731 participants who had a BMI of 30 or above, as well as heart failure with an ejection fraction of at least 50%