Debe respetarse la dosis indicada por el fabricante hasta que exista una aclaracin
Severe side effects include an increased risk of diabetes and certain cancers
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In the presence of the DAT inhibitor GBR12909, chronically stressed mice also exhibited less reward-directed behavior and attenuation of dopamine-mediated stimulatory effects on locomotor activity and NAc activation (Bergamini et al., 2018)
This suggests that the observed minor PK changes were not clinically relevant