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Treatment Schedule and Follow-Up Intralesional biologic injections are administered at 23-week intervals fora total of four treatment sessions (Weeks 0, 3, 6, and 9)
Figure 1 In addition, to fully determine the impact of LA on renal dysfunction induced by FA, the direct evaluation of renal function was determined with the indicators as displayed in Supplementary Table 1, FA injection markedly decreased urine volume, glomerular filtration rate (GFR), and filtration fraction compared with control mice, but these indexes could be reversed partially by LA supplementation, without obvious difference between the two dose groups
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Histone lactylation-derived LINC01127 promotes the self-renewal of glioblastoma stem cells via the cis-regulating the MAP4K4 to activate JNK pathway