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The preservative inhibits the growth of bacteria, which is what allows a sealed multi-dose vial to be entered with a sterile needle repeatedly typically over a 28-day in-use window without the remaining contents losing sterility

For this purpose, we utilized 4-hydroxy-2-nonenal (4-HNE), which is one of the major products of lipid peroxidation and can be used as a marker for oxidative stress 11,12,13

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