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Oxidized glutathione (GSSG) is recycled by glutathione reductase using NADPH

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Fu J, Zeng W, Chen M, Huang L, Li S, Li Z, Pan Q, Lv S, Yang X, Wang Y, Yi M et al (2022) Apigenin suppresses tumor angiogenesis and growth via inhibiting HIF-1 expression in non-small cell lung carcinoma

These results are noteworthy as it has been shown that NOS activity is necessary for calcium-induced activation of the Akt pathway

10.1159/000362826 36 FanL.FengY.ChenG

Glutathione assists the liver in processing environmental pollutants, heavy metals, medications, alcohol byproducts, and other compounds that place strain on metabolic pathways