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Researchers have found that counterfeit cigarettes can have as much as seven times the lead of authentic brands and close to three times as much thallium, a toxic heavy metal.[19] Other sources report finding insect eggs, dead flies, mold, and human feces in counterfeit cigarettes.[20] During the prohibition of alcohol in the United States during the 1920s, increased enforcement failed to significantly decrease the prevalence of bootlegging because the profit margins were so large and the distribution networks sophisticated

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Special efforts were made to discourage smokeless tobacco as a safer alternative to cigarettes, and one should assume that, if the claim Not Safer than cigarettes was scientifically defensible, it would have been made in the official warnings

A 2023 study of insurance claims data found no significant differences in the rates of psychosis-related diagnoses or prescribed antipsychotics in states with legal marijuana compared to those without

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