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this makes the process of weight loss and weight maintenance more difficult as it progresses

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GLP 1 acts in several ways: In the brain , it helps reduce hunger signals and quiets food noise , the constant mental chatter around eating In the gut , it slows gastric emptying, which prolongs the feeling of fullness This slower digestion contributes to weight loss, but it can also lead to constipation by increasing intestinal transit time Constipation is one of the most common side effects of GLP 1 medications

Address gaps in current research and the need for long-term studies These have major gaps including long term safety, dosing, delivery to ovarian tissue, and offspring effects

[DOI] [PMC free article] [PubMed] [Google Scholar] 222.Fan, B