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A compound acting on follicle growth has more to work with where follicles are still viable than where they're long dormant

Evaluation: Body fat (DXA scanning) Lean mass Insulin sensitivity Energy expenditure What they found: The combination showed an additive effect on fat reduction vs monotherapy AOD-9604 partially protected lean mass during GLP-1-induced weight reduction Increased energy expenditure in combination (~3 % vs GLP-1 alone) No new safety signals Why it matters: It validates the concept of combination , the idea that AOD-9604 may not work on its own, but can add value in combination with incretin agonists

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However, important population gaps exist in the published safety data

Other Studies Joint repair effect: In the rabbit collagenase-induced knee osteoarthritis model, AOD 9604 can promote cartilage regeneration, and the effect is better when combined with hyaluronic acid injection

DHT pathway