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Of the 12 patients, 8 had grade 3 or 4 thrombocytopenia
Composite specimens were prepared at room temperature (22 1 C) in disc-shaped Teflon moulds with a diameter of 6 mm and a height of 2 mm
The sample was centrifuged at 20200 g for 10 min at 4C, transferred to UPLC auto-sampler vials and analyzed according to the analytical method