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doi: 10.1080/15548627.2016.1187366 97 BaiYMengLHanLJiaYZhaoYGaoHet al

Mechanistically, statins altered the bile-acid pool (notably lowering ursodeoxycholic acid, UDCA), which reduced signaling through the TGR5 receptor on intestinal cells, leading to less GLP-1 release

[21] [22] Studies of progeroid (premature aging) syndromes, which mimic the clinical and molecular characteristics of aging, have provided some insight into the mechanism of action of NAD+ replenishment

J Cutan Med Surg

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