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For quantitative data obeying normal distribution, least significance difference (LSD) and Duncan's test of one-way analysis of variance (ANOVA) were used if the variance was homogeneous, and Dunnett's T3 test of one-way ANOVA was utilized to test the difference between multiple groups if the variance was not homogeneous, and the significance level was set at p 0.05) (Fig

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doi: 10.4049/jimmunol.175.6.3955 108 Nikolich-ZugichJ

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Participants were randomly assigned in a 1:1 ratio to receive either semaglutide 50 mg or a placebo once daily for 68 weeks

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