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Smoking was first linked to lung cancer in 1940 and the early 1950s

Quitting smoking cold turkey is a challenge that requires significant commitment and perseverance

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While the role of genetic mutations in carcinogenesis has been a widely accepted concept for several decades, it is only in the recent past that the key influence of the micro-environment on tumor growth and spread has been recognized and acknowledged

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Guidelines for Implementation of Article 5.3 of the WHO Framework Convention on Tobacco Control (2008)