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An open-label, randomized, controlled, crossover study to assess nicotine pharmacokinetics and subjective effects of the JUUL system with three nicotine concentrations relative to combustible cigarettes in adult smokers

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Although the symptoms of nicotine withdrawal can be uncomfortable, they show that the body is healing and returning to its normal state

Tobacco stains are common because of the nicotine and tar in tobacco products

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The symptoms can begin in just a few hours after the last use