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Initially we may have gut issues (reflux, bloating, cramping, diarrhoea), and if histamine breaks through gut to the bloodstream we may get hives, migraines, heart palpitations, anxiety, insomnia, and vertigo

It is a critical organ that is responsible for many functions vital to health and life ( 1 )

Eur J Pharmacol (2016) 783:2332

It plays a crucial role in postprandial glucose regulation and satiety signaling that is entirely separate from the incretin system

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For children and adolescents aged 2 to 18, providers assess BMI using a percentile scale based on gender and age, defining obesity as a BMI at or above the 95th percentile and overweight as falling between the 85th and 94th percentiles (3)