are tobacco and alcohol drugs Comparative risk assessment of alcohol, tobacco, cannabis other illicit using the margin of exposure approach Gateway Drugs – Marijuana, Tobacco

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Symptoms can include nausea, dizziness, and increased heart rate

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In contrast, nicotine replacement products (patch, gum, lozenges) release nicotine in a slow, controlled manner designed to be less addictive, and research has shown that they deliver much lower levels of nicotine to the body than tobacco products

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thus, it may be meaningful to classify CKD with the eGFR calculated by alternative equations because of the potential effects of non-renal factors on serum creatinine