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The semaglutide and cagrilintide mix creates combined effects because both peptides suppress appetite but through different brain pathways (hypothalamic GLP-1 receptors vs brainstem amylin receptors), both slow gastric emptying but through different receptor systems creating additive effects, both improve glucose control through paired mechanisms, and together provide more full body effects than either alone

Acknowledgments Funding: This research was supported by the Funds of the Natural Science Foundation of Hangzhou (2024SZRYBH180001) and Nanjing Medical University Fan Daiming Research Funds for Holistic Integrative Medicine

It is explicitly not intended for human consumption or therapeutic use

These studies positioned Epitalon as a promising therapeutic in the emerging field of biogerontology the science of aging at the molecular and cellular levels

Researchers may use it in controlled in vitro or laboratory settings to observe pathway behavior and compare related peptide activity under documented experimental conditions

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