This matters because many adults with low B12, whether from dietary restriction, aging, or conditions like pernicious anemia, cannot absorb enough B12 through food or oral supplements alone
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Withdrawal rates due to adverse effects serve as a practical measure of real-world tolerability, as they reflect whether side effects are bothersome enough to outweigh potential benefits
By increasing neurotransmitter activity, it creates a feeling of satiety, reducing overall calorie intake while also enhancing metabolic function