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Thus, for a 500mcg research concentration, 20 units (0.2ml) should be withdrawn
The major disadvantages of the aqueous liquid formulations are microbial contamination, chemical instability of the dissolved drug in aqueous conditions, presence of preservatives that may cause mucosal irritation, and short residence time in the nasal cavity due to mucociliary action [21]
However, it doesnt absorb well, and requires a methyl donor (a natural antidote and an antagonist for toxins) to detoxify it before it can convert to one of the useful forms of B12
Use is contraindicated in individuals with baseline hypoglycemia or conditions predisposing to hypoglycemia
Correct bacteriostatic water technique reduces contamination risks
The peptide shows particular promise for inflammatory bowel conditions
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