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Zhang Y., Marcillat O., Giulivi C., Ernster L., and Davies K

To determine whether these BAL fluid levels were a reflection of intracellular GSH metabolism, freshly brushed and isolated HAECs were analyzed and compared to BAL fluid levels (Figure 1B)

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Interestingly, the treatment demonstrated dose-dependent therapeutic effects, with moderate dosages proving more effective than high doses (1,000 mg/kg), possibly due to pharmacodynamic principles, where excessive concentrations saturate biological pathways and diminish therapeutic outcomes (Tyagi et al., 2025