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43 Epigenome-wide association studies (EWAS) have reported several epigenetic changes related to serum inflammatory markers suggesting a global hypomethylation of the genome during inflammation

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Mass spectrometry (MS) data should confirm this within normal instrument tolerance

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IGF-1, as a nutrient-responsive growth factor, activates NF-B and the expression of downstream genes (Ccdn1, Vegf, Birc5 and Ptgs2) to promote the growth of pancreatic cancer in vitro and in vivo (88)