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While the medication begins working at a molecular level within hours, most patients notice the first tangible effects within 24 to 72 hours after their shot

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How GLP-1 Medications Work GLP-1 receptor agonists help you lose weight through several mechanisms including reducing appetite and food cravings significantly, slowing stomach emptying so you feel full longer, improving blood sugar regulation and insulin sensitivity, and supporting sustainable weight loss without extreme dieting

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The four stages look like this

Kane says that newer drugs have given doctors more tools for treating people with type 2 diabetes