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An endogenous uncoupling and swelling agent in liver mitochondria and its enzymic formation

impaired fatty acid -oxidation metabolism and impaired branched-chain amino acid metabolism can lead to the accumulation of large amounts of acyl CoA

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van der Strate BW, Postma DS, Brandsma C-A, Melgert BN, Luinge M, Geerlings M, Hylkema MN, van den Berg A, Timens W, Kerstjens HaM: Cigarette smoke-induced emphysema: A role for the B cell