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Macrophages take up lipids and transform into foam cells, while mtDNA acts as DAMPs recognized by PRRs, promoting oxLDL internalization

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Then, blood was sampled in the abdominal aorta and centrifuged for 15 min at 2000 g to obtain serum, which was subsequently retained and preserved at 80 C for subsequent analyses

While not a magic solution, these injections can support weight loss efforts when combined with healthy eating and exercise