Novel Agents and Future Directions The therapeutic pipeline continues to expand with increasingly sophisticated mechanisms
It is the natural pigment responsible for giving many yellow and orange fruits, vegetables, and plants their vibrant color
Glucagon-like peptide-1 receptor agonist (GLP-1RA) is a new type of hypoglycemic agent that has been shown to regulate blood glucose levels, reduce inflammatory responses and oxidative stress, and regulate lipid metabolism, among other effects
evaluated retatrutide a once-weekly injectable agent targeting GLP-1, GIP, and glucagon receptors simultaneously across multiple doses in adults with obesity or overweight without type 2 diabetes
In countries like Denmark, home to Novo Nordisk (Ozempic and Wegovys manufacturer), there are concerns about economic over-reliance on the pharmaceutical sector, to the extent a recent article from the National Public Radio (NPR 2024) has questioned whether Denmark is developing into a pharma state based on the Novo Nordisks chokehold on the Danish economy
This may increase the risk of preventable complications such as diabetic foot ulcers, vision loss (from diabetic retinopathy), chronic kidney disease, heart attacks, and even strokes 1